hi, I'm

Aidos Taiyr

I am an engineer who builds things — medical imaging pipelines, protein-structure models, embedded control systems — and I go wherever the interesting technical problem is, not wherever the field boundary says I should stay.

I am passionate about solving interesting real life problems using computational methods.

Research Assistant, NU Med Tech Advisor, DS Club
Aidos Taiyr
Neuroimaging pipelines
Data preprocessing, anatomical and statistical brain template construction, and validation.
Structural biology
Graph neural networks, spatial features.
Embedded systems
Bare-metal C, sensor fusion, control loops.
Applied ML
Classical + deep models, benchmarking.
Sagittal MRI slice with probabilistic brain atlas segmentation overlay
01 · NU School of Medicine · Research project

Kazakh Female Brain Atlas

First female-specific structural MRI brain template for the Kazakh population, built from 55 T1-weighted subjects. Led the pipeline design, probabilistic atlas construction, and cross-template validation. The early results were written up as a preprint and the final version is in the process of being submitted for a journal publication.

Preprint
Riso-style illustration of a DNA double helix with a highlighted variant site
02 · NU Department of Biology

Genomic Variant Effect Prediction with AlphaGenome

Applied AlphaGenome biological deep learning framework to score candidate genomic variants for RNA and splicing effects, interpreting predictions across tissues as part of a computational biology literature review on ageing–cancer interplay.

GitHub
3D rendering of a protein surface with electrostatic potential and interface region highlighted
03 · Independent project

Geometry-Aware Protein-Protein Interface Prioritization

Designed and trained a custom 3-layer distance-weighted message-passing GNN over residue-level spatial graphs, built entirely from single-chain 3D structure — no partner chain, sequence alignments, or pretrained language models. Since interface residues are sparse, evaluated the model in a rank-based setting (PR-AUC, Precision@K, F1@K) with complex-level train/test splits to prevent leakage, benchmarking it against self-implemented logistic regression, random forest, and heuristic baselines on ~1,900 PDB complexes, with 3D case studies of top-ranked residues.

GitHub
IMU click board wired via ribbon cable to an STM32F411 mikromedia development board
04 · Independent project

Miniature AHRS on STM32F411

Bare-metal C on ARM Cortex-M4 — interrupt-driven sensor fusion, complementary filter, PID control loop — debugged without any UART tooling.

GitHub
Chest X-ray next to its Grad-CAM heatmap overlay highlighting the model's focus region
05 · Independent project

Pneumonia Detection Classifier

Fine-tuned ResNet-18/50 on 25,000+ DICOM chest X-rays with weighted loss for class imbalance; Grad-CAM heatmaps for interpretability. Best F1 0.6751, recall 0.7521, accuracy 0.84.

06 · Independent project

Predicting Term Deposit Subscriptions

XGBoost and a stacking ensemble (SVM + XGBoost → RF meta) on imbalanced bank marketing data. Stacking ensemble reached F1 0.5606, AUC 0.9102, recall 0.7115.

07 · Independent project

Breast Cancer Diagnostic Classifier

Reproducible scikit-learn SVM pipeline on the UCI Breast Cancer dataset, tuned via GridSearchCV. 96% accuracy, 97% precision, 95% recall.